Three-Dimensional Diffusion-Weighted Multi-Slab MRI With Slice Profile Compensation Using Deep Energy Model

Authors: Reza Ghorbani, Jyothi Rikhab Chand, Chu-Yu Lee, Mathews Jacob, Merry Mani

Abstract: Three-dimensional (3D) multi-slab acquisition is a technique frequently
employed in high-resolution diffusion-weighted MRI in order to achieve the best
signal-to-noise ratio (SNR) efficiency. However, this technique is limited by
slab boundary artifacts that cause intensity fluctuations and aliasing between
slabs which reduces the accuracy of anatomical imaging. Addressing this issue
is crucial for advancing diffusion MRI quality and making high-resolution
imaging more feasible for clinical and research applications. In this work, we
propose a regularized slab profile encoding (PEN) method within a Plug-and-Play
ADMM framework, incorporating multi-scale energy (MuSE) regularization to
effectively improve the slab combined reconstruction. Experimental results
demonstrate that the proposed method significantly improves image quality
compared to non-regularized and TV-regularized PEN approaches. The regularized
PEN framework provides a more robust and efficient solution for high-resolution
3D diffusion MRI, potentially enabling clearer, more reliable anatomical
imaging across various applications.

Source: http://arxiv.org/abs/2501.17152v1

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